Custom Microfluidic Molds

The original Mother Machine reference:

Ping Wang, Lydia Robert, James Pelletier, Wei Lien Dang, Francois Taddei, Andrew Wright, Suckjoon Jun “Robust Growth of Escherichia coli” Current Biology, 20 (12), 2010, 1099-1103.

Con-Science offers a broad range of nanofabrication services. Most of our products are developed specifically for our clients. Here in our web-shop we have collected examples of some of our more standard products.

For a free inquiry related to any of our services or products, please contact us by email or telephone.

T: +46 (0)738 92 08 67
E: info@con-science.se

Custom-designed molds based on the mother machine concept. 

We provide tight tolerances including sub-100 nm features and sub-100 nm overlay precision of different layers. Additionally, we can process several overlayed layers (a 3 layer structure is shown on the left).

Our team custom made a mold for prof. Jun’s group (the original inventor of the Mother Machine concept), which was lower cost and better performance than their original fabrication flow. They were very happy with what we provided to them and have been a repeat customer ever since. In a tweet, Suckjoon Jun made the following statement:

“We endorse them. We designed & ordered multiplex mothermachine from them about a year ago. They delivered an excellent product. The price was reasonable, certainly far less than what it cost us back in 2008 at Harvard for the first mothermachine. We will use them again.”

Examples from literature of use of ConScience fabricated Mother Machine devices:

Jones, D. et al. Kinetics Of dCas9 Target Search In Escherichia Coli. Science 2017, 357, 1420-1424.

Hammar, P. et al. Direct Measurement Of Transcription Factor Dissociation Excludes A Simple Operator Occupancy Model For Gene Regulation. Nature Genetics 2014, 46, 405-408.

Kipper, K. et al. Application Of Noncanonical Amino Acids For Protein Labeling In A Genomically Recoded Escherichia Coli. ACS Synthetic Biology2016, 6, 233-255.

Contact us for pricing:

Disclaimer

ConScience AB offers and sells custom nanofabrication services by request. ConScience AB makes no claim to copyrighted materials or methods externally provided and sells only services requested – which are tailored toward customer demands. ConScience AB performs custom nanofabrication within a wide spectrum of fields and therefore, cannot reasonably assess FTO upon every request. As such, ConScience AB operates in good faith with customers under the assumption that customers have rights to use all designs provided and requested. Upon entering into a contract with ConScience AB, the customer agrees to assume liability for the designs and methods provided.